Drug-induced cutaneous lupus erythematosus after 5 years of treatment with carbamazepine
Amerio, P.; Innocente, C.; Feliciani, C.; Angelucci, D.; Gambi, D.; Tulli, A.
European journal of dermatology EJD 16(3): 281-283
2006
ISSN/ISBN: 1167-1122 PMID: 16709494 Document Number: 598765
Drug-induced lupus is a disease, inducible by several drugs, that shares symptoms and laboratory characteristics with idiopathic lupus erythematosus. We report a case of carbamazepine-induced cutaneous lupus erythematosus which developed after 5 years of treatment in a patient who was on this medication because of an epileptic crisis after cranial trauma. Carbamazepine is a medication rarely implicated in drug-induced cutaneous lupus, moreover there are very few reports of such long periods between the start of therapy and the presentation of the clinical symptoms. We describe this case to emphasize the possibility of cutaneous lupus induction by carbamazepine even after many years of therapy.