Direct conversion from low-dose morphine to transdermal fentanyl: efficacy for cancer pain and quality of life
Yamazaki, M.; Aoki, T.; Tachibana, M.; Akashi, T.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 33(2): 217-221
2006
ISSN/ISBN: 0385-0684 PMID: 16484859 Document Number: 597048
The efficacy and QOL in a cancer pain patient who converted to transdermal fentanyl from low-dose morphine (n=5) or high-dose morphine (n=5) were retrospectively compared. Cancer pain control was evaluated by visual analogue scales (VAS) score. Patients switched from low-dose morphine demonstrated significantly better scales. The number of morphine rescues was also significantly less in the low-dose conversion group. In conclusion, conversion from low-dose morphine is useful for cancer pain control from the aspect of efficacy and QOL.