Imiquimod treatment of lentigo maligna to dermoscopic and histologic clearance
Lorentzen, H.F.; Weismann, K.
Ugeskrift for Laeger 167(39): 3696-3697
2005
ISSN/ISBN: 1603-6824 PMID: 16219219 Document Number: 594432
Imiquimod is an immune system-modifying drug that switches the immune system to a Th1 response, enabling it to defeat virus-infected and neoplastic cells. We report on a 94-year-old woman with a large lentigo maligna (LM) on her cheek whom we treated with imiquimod 5% cream. Dermoscopy was used to identify the most suspect areas of the lesion for biopsy and in follow-up. By week 19 the lesion was cleared, and no remnants of the lesion were seen by dermoscopy or histology. Published LM cases treated with imiquimod are reviewed.