Role of carboxypeptidase in regulation of fibrinolysis
Samokhin, A.A.; Kudinov, S.A.
Ukrains'kyi Biokhimichnyi Zhurnal 77(6): 8-15
2005
ISSN/ISBN: 0372-3909 PMID: 19618737 Document Number: 591623
The paper is devoted to analysis of the literature data about a recently described component of haemostasis system that posseses carboxypeptidase activity and is activated by thrombin. The history of investigation and isolation of the new carboxypeptidase, their properties and participation in inhibition of fibrinolysis reactions was considered. Data are cited about carboxypeptidase B level changes under different physiological conditions and possible methods of fibrinolysis reactions strengthening by means of influence on activity of that carboxypeptidase.