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Role of uncoupling proteins UCP1, UCP2 and UCP3 in energy balance, type 2 diabetes and obesity. Synergism with the thyroid

Zaninovich, A.A.

Medicina 65(2): 163-169

2005

ISSN/ISBN: 0025-7680
PMID: 16075814
Document Number: 591424
This article discusses the factors that influence energy expenditure, appetite and glucose metabolism. Focus is given on thyroid hormones and brown adipose tissue, which unique activity of heat production and dissipation through the action of uncoupling proteins. The importance of these concepts in understanding the mechanisms regulating energy balance and their use in the prevention or treatment of obesity and type 2 diabetes are considered.

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