Head tremor and progressive multifocal leukoencephalopathy in AIDS patients: report of two cases
Rieder, C.R.M.; Ziomkowski, S.C.
Arquivos de Neuro-Psiquiatria 63(1): 150-153
2005
ISSN/ISBN: 0004-282X PMID: 15830082 Document Number: 591411
Progressive multifocal leukoencephalopathy (PML) is caused by replication of JC virus in oligodendrocytes of immunocompromised patients. Common manifestations are focal motor and sensory deficits, gait abnormalities, speech and language disturbances, cognitive disorders, headache, and visual impairment. Although the occurrence of movement disorders is rare in PML, bradykinesia, rigidity, dystonia, myoclonic jerks and myoclonic ataxia have been described. Head tremor associated with PML has not been previously reported. We report two cases of PML in whom head tremor was present.