Morpho- and angiogenetic characteristics of uterine leiomyoma
Zaĭrat'iants, O.V.; Sidorova, I.S.; Levakov, S.A.; Levin, E.M.; Opalenov, K.V.
Arkhiv Patologii 67(3): 29-31
2005
ISSN/ISBN: 0004-1955 PMID: 16075609 Document Number: 590228
Ordinary and cellular leiomyomas of 147 patients (age 23 - 65 years) were studied histologically and immunomorphologically. Five females with rapidly growing tumors were operated after therapy with gonadotropines blockers. Variants with weak and pronounced proliferative activity of neoplastic myocytes and various activity of neoangiogenesis were distinguished. The latter may be either phases of development or different tumour types. Use of gonadotropine blockers inhibits myocyte proliferation and activates formation of stroma.