Membrane-selective electrodes for drug analysis. Note II
Bibire, N.; Dorneanu, V.
Revista Medico-Chirurgicala a Societatii de Medici Si Naturalisti Din Iasi 109(2): 426-430
2005
ISSN/ISBN: 0048-7848 PMID: 16607814 Document Number: 590122
Seven membrane-selective electrodes with PVC matrix and liquid-membrane for N-butylscopolamine with different electroactive materials are presented. These electrodes have a linear response in the concentration range of 10(-6) - 10(-2) M N-butylscopolamine bromide, with a detection limit between 4.58 x 10(-7)M and 1.09 x 10(-6)M. These electrodes were used with good results for quantitative assay by direct potentiometry and potentiometric titration of N-butylscopolamine bromide from pharmaceutical formulations. Recovery was between 95.50% and 99.20% for N-butylscopolamine bromide of injectable solutions.