Hyperglycaemia as an indicator of concurrent acute pancreatitis in fulminant hepatic failure associated with hepatitis B infection

Srinivasan, A.; Venkataraman, S.; Hansdak, S.G.; Abraham, O.C.; Mathai, D.

Singapore Medical Journal 46(5): 236-237

2005


ISSN/ISBN: 0037-5675
PMID: 15858694
Document Number: 589890
Pancreatitis occurring concurrently with fulminant hepatic failure (FHF) is primarily detected on autopsy and is seldom clinically apparent. We report a fatal case of FHF in a 25-year old woman which was related to acute hepatitis B infection. In this patient, hyperglycaemia. needing insulin infusions led to the detection of acute pancreatitis. FHF complicated by acute pancreatitis has a poor prognosis. A high index of suspicion is necessary for its diagnosis. The role of orthotopic liver transplantation and use of antiviral therapies need further evaluation in this situation.

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