Comparative experimental study of left colonic anastomoses in intestinal obstruction; the value of anastomoses protection with free peritoneal graft
Perju, D.; Târcoveanu, E.; Lupaşcu, C.
Revista Medico-Chirurgicala a Societatii de Medici Si Naturalisti Din Iasi 109(4): 781-786
2005
ISSN/ISBN: 0048-7848 PMID: 16610176 Document Number: 589632
The paper describes the concept of peritoneal graft used to reinforce the colo-colic anastomoses made in emergency conditions of left colic obstruction, experimentally induced by surgical ligature, on Wistar rats. The comparative study was done on 24 rats, divided in 3 groups: group A with colic anastomoses protected with peritoneal graft, group B with one-layer colic anastomoses and group C with two-layer colic anastomoses. After 8 days, 7 rats survived in group A, 2 rats in group B and 3 rats in group C. All surviving rats in groups B and C presented anastomotic leak with local peritonitis, while in group A the anastomosis were healed. For group A, bursting strength of the anastomosis was measured and the mean value found was 63.64 cmH2O. It was proved the importance of protecting the colic anastomosis with supplementary layers, which increase the mechanical resistance and also prevents minor spillage of the colic content during the first postoperative days.