Clinical evaluation of emergency liver transplantation for patients with benign end-stage liver diseases
Wang, W.-l.; Zheng, S.-s.; Xu, X.; Liang, T.-b.; Jin, J.; Shen, Y.; Zhang, M.; Wu, J.
Zhonghua Yi Xue Za Zhi 85(49): 3460-3463
2005
ISSN/ISBN: 0376-2491 PMID: 16686060 Document Number: 589529
To evaluate the efficacy of emergency liver transplantation in treating patients with benign end-stage liver diseases and explore the possible prognostic factors. The clinic data of 46 cases of recipients who underwent ELT were retrospectively analyzed. clinicopathological variables (including age, gender, etiology, serum creatinine, PT, INR, albumin, total bilirubin) were compared between the survival group (n = 32) and the dead group (n = 14). And the prognostic values of CTP and MELD score were analyzed. Higher serum creatinine level, MELD score and CTP score were found in the dead group, as compared to those in survival group. The survival rates among CTP or MELD categories showed significant difference. Three-and six months and one year survival rates of total recipients were 73.9% , 71.7% and 69.6% respectively. Emergency liver transplantation is an effective treatment to salvage patients in end-stage. Serum creatinine is the important prognostic factor to the posttransplant survival. MELD score system is more sensitive than CTP classification in predicting the prognosis.