St. John's wort
Lawvere, S.; Mahoney, M.C.
American Family Physician 72(11): 2249-2254
2005
ISSN/ISBN: 0002-838X PMID: 16342849 Document Number: 587970
St. John's wort has been used to treat a variety of conditions. Several brands are standardized for content of hypericin and hyperforin, which are among the most researched active components of St. John's wort. St. John's wort has been found to be superior to placebo and equivalent to standard antidepressants for the treatment of mild to moderate depression. Studies of St. John's wort for the treatment of major depression have had conflicting results. St. John's wort is generally well tolerated, although it may potentially reduce the effectiveness of several pharmaceutical drugs.