Surgical treatment for Nevin stage IV and V gallbladder carcinoma: report of 70 cases
Xiao, W-Dong.; Peng, C-Hong.; Zhou, G-Wen.; Wu, W-Ding.; Shen, B-Yong.; Yan, J-Qi.; Yang, W-Ping.; Li, H-Wei.
Hepatobiliary and Pancreatic Diseases International Hbpd Int 4(4): 589-592
2005
ISSN/ISBN: 1499-3872 PMID: 16286269 Document Number: 587467
The role of aggressive surgery for end-stage gallbladder carcinoma is controversial. This retrospective study was designed to evaluate the outcome of surgical treatment for Nevin stage IV and V gallbladder carcinoma at a single institution. A retrospective analysis was made on 70 patients with Nevin stage IV and V gallbladder carcinoma undergoing surgical treatment from January 1993 to June 2004. There were 22 cases of stage IV and 48 of stage V. Cholecystectomy was performed in 37 cases with a resection rate of 53%, 9 cases received radical resection, 13 extended radical resection, and 15 palliative resection. The curative resection rate was 31% and the morbidity rate was 36%. Postoperative 1-, 3-, 5-year survival rates of curative and palliative resection were 69%, 33%, 8% and 27%, 13%, 0, respectively (P<0.01). The 1- and 3-year survival rates of patients undergoing exploratory laparotomy only were 3% and 0, respectively. Nevin stage IV and V gallbladder carcinoma should be treated by aggressive surgery. Curative resection is promising in the improvement of long-term survival rate.