Adenine triphosphate-sensitive potassium channels: classification, structure and functions
Mokhort, M.A.; Lymarenko, I.V.
Fiziolohichnyi Zhurnal 51(1): 109-120
2005
ISSN/ISBN: 2522-9028 PMID: 15801208 Document Number: 585887
The review is dedicated to classification, structure and function of ATP-sensitive potassium channels. A general classification of K+ channels into families is based upon the primary amino acid sequence of the pore-forming subunits. The earliest classification of potassium channels was made according to the main mechanism of activation or opening of the channels. Activation of the voltage-sensitive channels is regulated by changes in the membrane potential, and of the ligand-sensitive channels by a number of ligands (calcium ions, ATP, neurotransmitters and G-protein).