Priapism and activated protein C resistance
Guichard, G.; Henry, P.C.; Bittard, H.; Kleinclauss, F.ço.
Progres en Urologie Journal de l'Association Francaise d'Urologie et de la Societe Francaise d'Urologie 15(2): 337-338; Discussion 338
2005
ISSN/ISBN: 1166-7087 PMID: 15999622 Document Number: 585596
Priapism is a rare disease that can be secondary to a clotting disorder. The authors report the first published case of priapism due to a heterozygous mutation of factor V Leiden responsible for activated protein C resistance in a patient treated with low molecular weight heparin. A similar case has already been reported, but with a homozygous mutation. Priapism must therefore be considered to be a thromboembolic event and the presence of a clotting disorder should be systematically investigated in the absence of an obvious aetiology.