Whipple's disease with neurological manifestations: case report
França, M.C.; Castro, R.de.; Balthazar, Márcio.Luiz.F.; Malveira, G.Linard.S.; Pirani, C.; Deus-Silva, L.; Paz, A.R.da.; Queiroz, L.S.; Damasceno, B.P.
Arquivos de Neuro-Psiquiatria 62(2a): 342-346
2004
ISSN/ISBN: 0004-282X PMID: 15235743 Document Number: 584164
Whipple's disease (WD) is an uncommon multisystem condition caused by the bacillus Tropheryma whipplei. Central nervous system involvement is a classical feature of the disease observed in 20 to 40% of the patients. We report the case of a 62 year old man with WD that developed neurological manifestations during its course, and discuss the most usual signs and symptoms focusing on recent diagnostic criteria and novel treatment regimens.