Multimodal imaging of somatosensory evoked cortical activity
Ramon, C.; Haueisen, J.; Richards, T.; Maravilla, K.
Neurology and Clinical Neurophysiology Ncn 2004: 96
2004
ISSN/ISBN: 1526-8748 PMID: 16012632 Document Number: 583257
Somatosensory evoked cortical activity is well investigated in both fMRI and MEG/EEG. Investigation with functional magnetic resonance spectroscopic (fMRS) imaging is relatively new and provides a means to image the metabolic activity of the brain. We for the first time combined fMRS, fMRI, MEG and EEG. This provides information about the metabolic, hemodynamic and electrical activity of the brain and also the verification of one imaging modality with the other. The dipolar source localized from the EEG/MEG data is in the vicinity of the fMRI activation site and also in the same area where lactate consumption is high as measured with fMRS imaging.