Molecular epidemiology of β-lactamase-producing Neisseria gonorrhoeae strains in Manaus, AM, Brazil
Ferreira, W.A.; Ferreira, C.M.; Naveca, F.G.; de Souza Vasconcelos, W.; de Souza Gomes, J.; da Silva, M.d.F.át.P.; Alecrim, M.d.G.ça.C.
Sexually Transmitted Diseases 40(6): 469-472
2013
ISSN/ISBN: 1537-4521 PMID: 23680903 DOI: 10.1097/olq.0b013e318286d2ceDocument Number: 581722
We report new sequence types of 14 penicillinase-producing Neisseria gonorrhoeae, isolated from sexually transmitted disease clinic attendees in Manaus, Brazil. They were characterized by WI/WII/WIII groups, susceptibility testing and Multi-Antigen Sequencing Typing/Mutilocus Sequence Typing protocols. Twelve were classified as WII/III and 2 as WI and were presented resistance to penicillin and tetracycline. New alleles for por and AroE genes and novel sequence types were identified, revealing molecular characteristics not described previously. ST1590 is the common ancestor after eBURST analysis, and these findings represent an important contribution of molecular epidemiology approach in gonococci's research in Amazonas.