Effects of modified anaesthesia for patients undergoing brain artery aneurysm repair operation
Grabowska-Gaweł, A.; Wiśniewski, J.
Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego 17(99): 248-251
2004
ISSN/ISBN: 1426-9686 PMID: 15628051 Document Number: 579461
55 patients (age 45-63 years old) scheduled for elective brain artery anaeurysm repair operation were randomly divided into two groups: thiopental, atracurium besilate and fentanyl group (group I; n= 27) and propofol, vecuronium bromide and fentanyl in a continuous intravenous administration group (group II; n=28). In group II little changes of arterial blood pressure during the operation were observed. Also the mean time for patient's awaiking was significantly shorter which allowed effective postoperative evaluation of neurological status. In group II only 1 patient required administration of urapidil and in group I 11 ( 40.7%) of patients required lowering blood pressure treatment. There were 7 cases of intra-operative aneurysm ruptures and 5 cases of brain artery embolism not significantly associated with anaesthesia given. It is of a high importance to maintain intraoperatively normal blood pressure, normal blood oxigenation, normal fluid administration and normal blood carbon dioxide levels.