Gestodene: a review of its pharmacology, potency and tolerability in combined contraceptive preparations
Stanczyk, F.Z.; Archer, D.F.
Contraception 89(4): 242-252
2014
ISSN/ISBN: 1879-0518 PMID: 24485094 DOI: 10.1016/j.contraception.2013.12.003Document Number: 578966
Combined progestin-estrogen pills are an established and reliable contraceptive option used by women worldwide. Combined oral contraceptives (COCs) containing the progestins--gestodene, desogestrel or norgestimate--were developed to minimize androgenic side effects and are considered an effective, well-tolerated contraceptive option. Gestodene achieves contraceptive efficacy with the lowest dose of any progestin in a COC, and has an established and favorable short- and long-term tolerability profile. In this review we present an overview of the pharmacology, potency and tolerability of gestodene.
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