Levonorgestrel intrauterine system as a treatment option for severe menorrhagia in adolescent with type IIi von Willebrand disease
Silva, C.D.; Geraldes, F.; Silva, I.S.
BMJ Case Reports
2013
ISSN/ISBN: 1757-790X PMID: 23632610 DOI: 10.1136/bcr-2013-008833Document Number: 578925
The authors describe a case of an adolescent with type III von Willebrand disease and severe menorrhagia since menarche. Antifibrinolytic, hormonal (estroprogestative pill in high doses, etonogestrel implant and gonadotropin-releasing hormone agonist goserelin) and Von Willebrand Factor/Factor VIII replacement therapies were prescribed to the patient, but symptomatic control was only obtained with high doses of VWF/FVIII twice a week. In March 2012, a levonorgestrel intrauterine system was inserted in a 14-year-old. At present, the patient is asymptomatic without regular prophylaxis (VWF/FVIII replacement therapy) and has had a remarkable improvement in her quality of life.