Plasma efavirenz in HIV infected children treated with generic antiretroviral drugs in India
Ramachandran, G.; Kumar, A.K.H.; Vasantha, M.; Shah, I.; Swaminathan, S.
Indian Pediatrics 47(10): 890-891
2010
ISSN/ISBN: 0974-7559 PMID: 21048244 Document Number: 578436
We measured plasma concentration of efavirenz (EFV) in 16 HIV-infected Indian children receiving antiretroviral treatment at Government ART centres. The mean 12 hour concentration was 2.39 ug/mL (range: 0.72- 7.82 ug/mL). The majority of children treated with generic EFV at currently recommended doses had blood levels within the therapeutic range.
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