Prostatic cancer in a young adult: a report of 2 cases
Sasaki, H.; Miki, J.; Hasegawa, T.; Hasegawa, N.; Ikemoto, I.; Ohishi, Y.
Hinyokika Kiyo. Acta Urologica Japonica 50(1): 57-59
2004
ISSN/ISBN: 0018-1994 PMID: 15032019 Document Number: 577672
Patients younger than 45 years with prostate cancer are rare. Between 1999 and 2002, we studied two cases of prostate cancer in men aged under 45 years. Case I; a 45-year-old man admitted with the chief complaint of urination disorder. Serum level of prostate-specific antigen (PSA) was 5,000 ng/ml or higher. Transrectal needle biopsy of the prostate revealed moderately differentiated adenocarinoma. Computed tomography (CT) and hone scan showed para-aorta lymph node metastasis and hone metastasis. Hormone therapy was performed. Case 2; a 37-year-old man admitted with the chief complaint of pollakisuria and sense of residual urine. Serum level of prostate-specific antigen (PSA) was 24 ng/ml. Magnetic resonance imaging (MRI) showed that the prostate tumor invaded the bladder wall. Transrectal needle biopsy revealed poorly differentiated adenocarcinoma. Hormone therapy and radiation therapy were performed. Twenty-one cases reported in Japan in addition to the present cases are reviewed.