Mortality among HIV/AIDS patients coinfected with Mycobacterium tuberculosis in southern Thailand
Chaimay, B.; Woradet, S.; Chantutanon, S.; Phuntara, S.; Suwanna, K.
Southeast Asian Journal of Tropical Medicine and Public Health 44(4): 641-648
2013
ISSN/ISBN: 0125-1562 PMID: 24050098 Document Number: 576742
The purpose of this study was to investigate the mortality rate among HIV/AIDS patients coinfected with Mycobacterium tuberculosis in southern Thailand. A prospective, hospital-based cohort study was conducted among 52,459 HIV/AIDS patients registered at hospitals in 14 provinces of southern Thailand between January 1990 and April 2010. Twenty-seven point nine percent of the subjects were coinfected with Mycobacterium tuberculosis. Coinfection with Mycobacterium tuberculosis was not significantly associated with an increased mortality among subjects (HR 1.01; 95%CI 0.96-1.05). Subjects with pulmonary tuberculosis infection were 19% more likely to have a longer life (HR 0.81, 95%CI 0.73-0.91) and subjects with extrapulmonary tuberculosis were 31% more likely to have a longer life (HR 0.69; 95%CI 0.57-0.83). Early treatment of tuberculosis in HIV/AIDS patients can decrease mortality rates in southern Thailand.