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Experience with granulocytapheresis in Crohn's disease

Cuenca, F.; García Paredes, J.; Mendoza, J.L.; Cruz, D.M.; Herrero, A.; Díaz-Rubio, M.

Revista Espanola de Enfermedades Digestivas Organo Oficial de la Sociedad Espanola de Patologia Digestiva 96(7): 501

2004

ISSN/ISBN: 1130-0108
PMID: 15283632
Document Number: 573415
Objective: to describe our experience with granulocyte apheresis to induce remission in patients with active Crohn's disease refractory to conventional treatment. We summarize the results previously obtained with this technique. Conclusions: granulocyte apheresis is a safe and well tolerated therapeutic modality that can be a valid therapeutic alternative in the induction of remission in inflammatory bowel disease, although controlled clinical trials must be conducted to define long-term efficacy, as well as to establish "optimal patient" selection, re-treatment interval, and number of sessions.

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