Prevalence of transmitted HIV-1 drug resistance mutations in children and adolescents in São Paulo, Brazil

Almeida, F.áv.J.; Rodrigues, R.; Zaparoli, M.S.; Berezin, E.N.; Sáfadi, M.A.él.P.; de Paula Ferreira, J.ão.L.; Lança, A.é M.; de Macedo Brígido, L.F.

Pediatric Infectious Disease Journal 31(12): E255-E257

2012


ISSN/ISBN: 1532-0987
PMID: 23188105
DOI: 10.1097/inf.0b013e3182684d8e
Document Number: 572966
HIV drug resistance genotype testing, performed on 39 HIV-infected treatment-naive children from 2000 to 2011, identified 5 children (12.8%) with drug resistance mutations: 5.3% to nucleoside reverse transcriptase inhibitors, 5.3% to nonnucleoside reverse transcriptase inhibitors and 7.7% to protease inhibitors. There was a trend for increasing prevalence of drug resistance mutations during the 11-year study period.

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