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Effect of centrifuge-induced artificial gravity and ergometric exercise on cardiovascular deconditioning, myatrophy, and osteoporosis induced by a -6 degrees head-down bedrest

Iwase, S.; Takada, H.; Watanabe, Y.; Ishida, K.; Akima, H.; Katayama, K.; Iwase, M.; Hirayanagi, K.; Shiozawa, T.; Hamaoka, T.; Masuo, Y.; Custaud, M.-A.

Journal of Gravitational Physiology a Journal of the International Society for Gravitational Physiology 11(2): P243-P244

2004

ISSN/ISBN: 1077-9248
PMID: 16240530
Document Number: 572707
We have reported that centrifuge-induced artificial gravity with ergometric exercise could reduce developing cardiovascular deconditioning in humans. In the present study, we examined this load could prevent the myatrophy and osteoporosis induced by head-down bedrest for 20 days. Subjects were ten healthy male volunteers with informed consent. They were requested to lie down at -6 degrees for 20 days, and evaluation for cardiovascular deconditioning, myatrophy, and osteoporosis. As the result, high G-load with low intensity exercise suppressed the orthostatic intolerance and increase in serum osteoporotic marker, whereas low G-load with high intensity ergometric exercise maintained the maximal oxygen intake, heart dimension, and prevented myatrophy. The combination of high/low G-load with low/high intensity exercise will determine the optimal protocol for prevention of cardiovascular deconditioning, myatrophy, and osteoporosis.

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Haruna, Y.; Takenaka, K.; Suzuki, Y.; Kawakubo, K.; Gunji, A. 1998: Effect of acute saline infusion on the cardiovascular deconditioning after 20-days head-down tilt bedrest Journal of Gravitational Physiology: a Journal of the International Society for Gravitational Physiology 5(1): P45-P46
Butler, G.C.; Xing, H.C.; Hughson, R.L. 1990: Cardiovascular response to 4 hours of 6 degrees head-down tilt or of 30 degrees head-up tilt bed rest Aviation Space and Environmental Medicine 61(3): 240-246
Rosene, J.M.; Rosene, J.A.; Koczajowski, D.L.; Paolone, V.J. 1999: Decongestant effects on hemodynamics at rest, exercise, and recovery from exercise during--6 degrees of head down tilt Aviation Space and Environmental Medicine 70(1): 15-21
Sarkisov, I.Iu.; Shipov, A.A. 1975: Eye movements occurring during head rotation on artificial gravity stands Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina 9(6): 3-8
Zborovskaya, V.I. 1979: Use of a short-radius centrifuge to prevent deconditioning during immersion in water (according to the H-reflex) Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina 13(5): 78-79
Mitchell, J.B.; Flynn, M.G.; Goldfarb, A.H.; Ben-Ezra, V.; Copmann, T.L. 1990: The effect of training on the norepinephrine response at rest and during exercise in 5 degrees and 20 degrees C environments Journal of Sports Medicine and Physical Fitness 30(3): 235-240
Van den Broek, L.; Proost, J.H.; Wierda, J.M.; Njoo, M.D.; Hennis, P.J. 1994: Neuromuscular and cardiovascular effects of neostigmine and methyl-atropine administered at different degrees of rocuronium-induced neuromuscular block European Journal of Anaesthesiology 11(6): 481-487
Bernauer, E.M.; Walby, W.F.; Ertl, A.C.; Dempster, P.T.; Bond, M.; Greenleaf, J.E. 1994: Knee-joint proprioception during 30-day 6 degrees head-down bed rest with isotonic and isokinetic exercise training Aviation Space and Environmental Medicine 65(12): 1110-1115
Maignan, E.; Martel, E.; Safar, M.; Cuche, J.L. 2000: Norepinephrine kinetics in the rat with tail-suspension-induced central hypervolemia, as a model of cardio-vascular deconditioning Journal of Gravitational Physiology: a Journal of the International Society for Gravitational Physiology 7(2): P141-P142
Kido, R.; Matsumoto, T. 2012: Space flight/bedrest immobilization and bone. Signaling cascade induced by mechanical stress Clinical Calcium 22(12): 1837-1843
Whinnery, A.M.; Whinnery, J.E.; Hickman, J.R. 1990: High +Gz centrifuge training: the electrocardiographic response to +Gz-induced loss of consciousness Aviation Space and Environmental Medicine 61(7): 609-614
Hori, M.; Takahashi, H.; Konno, T.; Inoue, J.; Haba, T.; Sakurada, T.; Noda, T.; Fujimoto, K. 1984: Effect of elcatonin on experimental osteoporosis induced by ovariectomy and low calcium diet in beagles Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica 84(1): 91-98
Kaczmarczyk-Sedlak, I.; Wojnar, W.; Zych, M.; Ozimina-Kamińska, E.; Bońka, A. 2016: Effect of Dietary Flavonoid Naringenin on Bones in Rats with Ovariectomy-Induced Osteoporosis Acta Poloniae Pharmaceutica 73(4): 1073-1081
Hu, B.; Li, Q.; Li, C.; Wu, T.; Huang, L. 1999: Skeletal effect of xianzhen gubao on preventing prednisone-induced osteoporosis in male rats Zhongguo Zhong Yao Za Zhi 24(9): 559-61 576
Robin, J.C.; Sirianni, S.R.; Pragay, D.A.; Ambrus, J.L. 1981: Studies on osteoporosis. V. Comparison of methods of evaluation of osteoporosis and study of chromosome changes induced by neutron activation Journal of Medicine 12(4): 251-256
Suzuki, Y.; Wakabayashi, T. 2015: Management of osteoporosis associated with rheumatoid arthritis and glucocorticoid-induced osteoporosis Clinical Calcium 25(12): 1825-1834
Pilger, E.; Schmid, P.; Goebel, R. 1979: Effect of biguanids on the lactate metabolism. Studies in diabetics under submaximal ergometric exercise Medizinische Klinik 74(22): 859-865
Syc, S. 1971: Causes of cortisol-induced osteoporosis and Cushing's disease osteoporosis Wiadomosci Lekarskie 24(1): 41-43
Aronow, W.S.; Isbell, M.W. 1973: Carbon monoxide effect on exercise-induced angina pectoris Annals of Internal Medicine 79(3): 392-395
Stenius, B.; Salorinne, Y.; Parrott, D. 1978: The effect of inhaled RS 7540, a xanthone, on exercise-induced asthma Scandinavian Journal of Respiratory Diseases 59(2): 75-81