Mobile device for disease diagnosis and data tracking in resource-limited settings
Guo, T.W.; Laksanasopin, T.; Sridhara, A.A.; Nayak, S.; Sia, S.K.
Methods in Molecular Biology 1256: 3-14
2015
ISSN/ISBN: 1940-6029 PMID: 25626528 Document Number: 571609
Here we describe a low-cost mobile device that combines cell-phone and satellite communication technologies with fluid miniaturization techniques for performing all essential functions of enzyme-linked immunosorbent assay (ELISA). Disease-specific antigens are immobilized on the microfluidic surface, and disease specific antibodies are captured on the surface and visualized with silver-gold amplification. The diagnostic result is automatically determined by the device by measuring the absorbance through the silver-gold amplification in the microchannel. The results are displayed for the user and are synchronized to a remote patient record. The overall system aims to be portable, robust, low-power, and fully utilize the ability of mobile devices for bringing better health care to resource poor areas.