Cross-reactions between the antigens of healthy pulmonary tissue and Moraxella catarrhalis
Markina, O.A.; Iastrebova, N.E.; Vaneeva, N.P.; Liashova, V.N.; Ovechko, N.N.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 2004(4): 40-43
2004
ISSN/ISBN: 0372-9311 PMID: 15481918 Document Number: 569931
The study of cross-reactions between healthy pulmonary tissue antigens and Moraxella catarrhalis with the use of SDS-electrophoresis and immunoblotting revealed that in the component of healthy pulmonary tissue with a mol. wt. of 40 kD epitopes existed to which antibodies were produced,, capable of cross reaction with the components of M.catarrhalis with a mol. wt. of 35 kD and 70 kD. In addition, the presence of cross-reactions between cytokeratin-8, protein contained in healthy pulmonary tissue, and M.catarrhalis antigens was established.