The use of freeze-dry bovine pericardium (FDBP) in diaphragmatic herniorrhaphy in dogs
Loqman, M.Y.; Wong, C.M.; Hair-Bejo, M.; Zuki, A.B.Z.; Hafeez, Y.M.
Medical Journal of Malaysia 59(Suppl): 113-114
2004
ISSN/ISBN: 0300-5283 PMID: 15468844 Document Number: 569516
This study was conducted to investigate the effectiveness of freeze dried bovine pericardium (FDBP) as a biomaterial in diaphragmatic herniorrhaphy in dogs. A total of 8 adult dogs were randomly selected and divided into 2 groups. In the FDBP group, a diaphragmatic defect was induced and repaired with an identical size of FDBP. In the control group, a diaphragmatic wall was incised at the 3-side border creating a flap and was sutured. Grossly, only mild intrathoracic adhesion was observed in most animals, and no herniation, occurred. Microscopically, the biomaterial incorporated into the host's tissue by ingrowth of young muscle fibres and massive new blood vessel formation in between the fibrous tissue.