The role of endocrine therapy in early breast cancer: adjuvant treatment of preand postmenopausal patients
Nesković-Konstantinović, Z.; Filipović, S.
Journal of Buon Official Journal of the Balkan Union of Oncology 8(1): 11-17
2003
ISSN/ISBN: 1107-0625 PMID: 17415861 Document Number: 566380
Two major trends are evident from ongoing conferences and panels of experts on early breast cancer adjuvant treatment. The first strongly suggests the application of wellestablished standards of adjuvant treatment in everyday clinical practice. The second encourages participation in international adjuvant clinical studies of breast cancer. Our growing knowledge of the role of endocrine adjuvant therapy in early breast cancer has emerged from the findings of large adjuvant studies. Meta-analyses of numerous randomised trials have accumulated evidence that has been analysed on many occasions by international panels of experts and has become a major source of consensus recommendations. Nevertheless, many open questions still exist, and new ones arise. This paper reviews the current standards for the adjuvant treatment of endocrine-dependent breast cancer, as well as some perspectives emerging from ongoing clinical studies.