Top Abstract Purchase Related
Home
>
Node
>
Subnode

Cellular and molecular changes of the liver in sepsis and in systemic inflammatory response syndrome (SIRS)

Romics, L.ás.ó; Frendl, G.ör.; Szabó, G.ön.

Orvosi Hetilap 144(11): 499-506

2003

ISSN/ISBN: 0030-6002
PMID: 12731336
Document Number: 566182
This paper provides a review on the changes in the molecular and cellular level of the liver during sepsis and systemic immune response syndrome. The different function of the various liver cells and their mediators are analyzed. Dual role of nitric-oxide and carbon-monoxide are discussed followed by an overview about acute phase proteins and heat shock proteins in septic liver. A detailed description is presented on the role of the Toll-like receptors and their signaling pathways in the liver during sepsis and systemic immune response syndrome. Finally, the possible mechanisms leading to apoptosis of the liver cells are shown and the most recent therapeutical challenges are discussed.

Document emailed within 1 workday
Secure & encrypted payments

Hryckiewicz, K.; Juszczyk, J.; Samet, A.; Arłukowicz, E.; Sledzińska, A.; Bolewska, B. 2006: Procalcitonin as a diagnostic marker in systemic inflammatory response syndrome (SIRS) and sepsis Przeglad Epidemiologiczny 60(1): 7-15
Dadeh, A-aishah.; Wuthisuthimethawee, P. 2016: Serum Lactate Levels as a Prognostic Predictor of Septic Shock in Emergency Department Patients with Systemic Inflammatory Response Syndrome (SIRS) at Songklanagarind Hospital Journal of the Medical Association of Thailand 99(8): 913-918
Shano, V.P.; Nesterenko, A.N.; Giul'mamedov, F.I.; Giul'mamedov, P.F. 1998: Sepsis and the systemic inflammatory response syndrome Anesteziologiia i Reanimatologiia 4: 60-64
Gritsuk, S.F.; Bezrukov, V.M.; Shafranskiĭ, A.P. 2000: Systemic inflammatory response syndrome and sepsis in maxillofacial surgery clinic Khirurgiia 1: 47-53
Kreimeier, U.; Peter, K. 1998: Strategies of volume therapy in sepsis and systemic inflammatory response syndrome Kidney International. Supplement 64: S75-S79
Galstian, G.M.; Gorodetskiĭ, V.M.; Vasil'ev, S.A.; Isaev, V.G.; Orel, E.B.; Kliasova, G.A.; Danilina, A.V. 1998: Criteria of systemic inflammatory response syndrome are unacceptable in the diagnosis of sepsis in patients with leukopenia Anesteziologiia i Reanimatologiia 6: 72-76
Koc, B.; Oktenli, C.; Bulucu, F.; Karadurmus, N.; Sanisoglu, S.Yavuz.; Gul, D. 2007: The rate of pyrin mutations in critically ill patients with systemic inflammatory response syndrome and sepsis: a pilot study Journal of Rheumatology 34(10): 2070-2075
Ayoglu, H.; Sezer, U.; Akin, M.; Okyay, D.; Ayoglu, F.; Can, M.; Kucukosman, G.; Piskin, O.; Aydin, B.; Cimencan, M.; Gur, A.; Turan, I. 2016: Selenium, copper, zinc, iron levels and mortality in patients with sepsis and systemic inflammatory response syndrome in Western Black Sea Region, Turkey Jpma. Journal of the Pakistan Medical Association 66(4): 447-452
Fry, D.E. 2012: Sepsis, systemic inflammatory response, and multiple organ dysfunction: the mystery continues American Surgeon 78(1): 1-8
Ono, S.; Ichikura, T.; Mochizuki, H. 2003: The pathogenesis of the systemic inflammatory response syndrome and compensatory antiinflammatory response syndrome following surgical stress Nihon Geka Gakkai Zasshi 104(7): 499-505
Takakuwa, T.; Endo, S.; Inada, K.; Kasai, T.; Yamada, Y.; Ogawa, M. 1997: Assessment of inflammatory cytokines, nitrate/nitrite, type Ii phospholipase A2, and soluble adhesion molecules in systemic inflammatory response syndrome Research Communications in Molecular Pathology and Pharmacology 98(1): 43-52
Yachnyk, I.M. 2015: Diagnostic Estimate of a C-Reactive Protein in Differential Diagnosis of Sepsis and Syndrome of Systemic Inflammatory Answer Klinichna Khirurhiia 9: 33-35
Aikawa, N.; Fujishima, S. 2004: Understanding the pathogenetic mechanisms of SIRS and sepsis and development of innovative therapies of sepsis Nihon Rinsho. Japanese Journal of Clinical Medicine 62(12): 2173-2176
Huang, Y. 1996: Systemic inflammatory response syndrome Zhonghua Yi Xue Za Zhi 76(8): 629-631
Ніколєнко, Дмитро Є; Бойко, Дмитро М 2017: Analysis of the cellular composition and of the inflammatory response activity in the lymph nodes of patients with sarcoidosis at different stages of the clinical course and treatment with systemic glucocorticosteroids Wiadomosci Lekarskie 70(1): 32-37
De La Motte, L.; Vogt, K.; Panduro Jensen, L.; Groenvall, J.; Kehlet, H.; Veith Schroeder, T.; Lönn, L. 2011: Incidence of systemic inflammatory response syndrome after endovascular aortic repair Journal of Cardiovascular Surgery 52(1): 73-79
Godoy, D.; Boccio, A.; Hugo, N. 2002: Systemic inflammatory response syndrome and primary of spontaneous intracerebral haemorrhage Revista de Neurologia 35(12): 1101-1105
Baltodano, A. 1996: The systemic inflammatory response syndrome: its classification, physiopathology and treatment strategies Anales Espanoles de Pediatria 44(5): 414-421
Avdeeva, M.G.; Shubich, M.G. 2003: Pathogenetic mechanisms of the initiation of systemic inflammatory response syndrome (a literature review) Klinicheskaia Laboratornaia Diagnostika 2003(6): 3-10
Spack, L.; Havens, P.L.; Griffith, O.W. 1997: Measurements of total plasma nitrite and nitrate in pediatric patients with the systemic inflammatory response syndrome Critical Care Medicine 25(6): 1071-1078