Breakthrough neurological manifestation during appropriate antituberculous therapy of miliary tuberculosis
Lolekha, R.; Chokephaibulkit, K.; Vanprapar, N.; Phongsamart, W.; Chearskul, S.
Southeast Asian Journal of Tropical Medicine and Public Health 34(3): 634-635
2003
ISSN/ISBN: 0125-1562 PMID: 15115142 Document Number: 565365
We report a 20-month-old girl with miliary pulmonary tuberculosis and normal neurological findings. While on treatment with isoniazid, rifampicin, pyrazinamide, and ethambutol for 1 month, she developed weakness of the lower extremities without meningism or altered consciousness. A computerized tomogram revealed tuberculomas and basal arachnoiditis. The cerebrospinal fluid findings were compatible with tuberculous meningitis. She responded well to systemic corticosteroids.