Sex factors in effects of aerogenic toxic substances on the duration of hexenal-induced sleep
Inoiatov, F.S.
Fiziolohichnyi Zhurnal 49(1): 76-80
2003
ISSN/ISBN: 2522-9028 PMID: 12669524 Document Number: 564206
Inhalant poisoning with low doses of toxicants during 3 months resulted in slowing the biotransformation of hexenal in male rats, whereas lead acetate and sulphur dioxide were less active. Unlike the male rats, phenol in female ones prolonged hexenal-induced dream. Ammonia did not effect the biotransformation, whereas formaldehyde, lead acetate and sulphur dioxide accelerated it. Sex--linked dimorphism of MOS has been suggested to determine more pronounced hepatotoxicity of the compounds under exploration in male rats.