Ductal carcinoma in situ: current anatomo-pathologic data
Fiche, M.
Revue Medicale de la Suisse Romande 123(5): 295-298
2003
ISSN/ISBN: 0035-3655 PMID: 15095712 Document Number: 564046
Ductal carcinoma in situ (DCIS), accounting for 15-25% of all breast cancers, is frequently diagnosed by mammographic examination. This heterogeneous disease requires a rigorous local treatment based, in about two-third of cases, on conservative surgery and radiotherapy. DCIS are currently classified on the basis of nuclear grade. Most lesions, and especially high nuclear grade DCIS, are limited to one quadrant. Micropapillary DCIS are likely to be of larger size/extent and thus a conservative approach is often difficult. A careful pathological examination of an oriented excisional biopsy is a pre-requisite for optimal therapy.