Postoperative superficial hemosiderosis of the brain, its diagnosis, treatment and prevention

Rasmussen, T.

Transactions of the American Neurological Association 98: 133-137

1973


ISSN/ISBN: 0065-9479
PMID: 4784920
Document Number: 5638
Superficial cerebral hemosiderosis was first reported as a late complication of cerebral hemispherectomy by Ulrich, Isler, and Vasalli in 1965, and by Oppenheimer and Griffiths in 1966, but the condition was initially described in 1940 by Noetzel, who reported its occurrence in 2 patients with repeated subaracbnoid bleeding due to metastatic carcinoma of the leptomeninges in one patient and occurring without obvious cause in the other. In 1960, Iwanowski and Olszewski reproduced the condition experimentally in dogs by repeated intrathecal injections of autogenous blood and also by injection of a dextron-iron complex (Imferon). Falconer and Wilson, in 1969, reported the development of this complication in 4 patients out of a series of 18 with complete hemispherectomy.

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Postoperative superficial hemosiderosis of the brain, its diagnosis, treatment and prevention