Primary central nervous system lymphoma in a patient with systemic lupus erythematosus
Pisoni, C.N.; Grinberg, A.R.; Plana, Jé.L.; Freue, R.D.; Manni, J.A.; Paz, L.
Medicina 63(3): 221-223
2003
ISSN/ISBN: 0025-7680 PMID: 12876906 Document Number: 561351
A 36 year-old woman with systemic lupus erythematosus was admitted to our hospital with headache, brachiocrural hemiparesis and hemianesthesia. She had been treated with prednisone and cyclophosphamide. CT scan and MRI revealed a 15 mm nodular mass enhanced with gadolinium in left frontal convexity. CNS biopsy was performed and a diffuse large B-cell lymphoma was diagnosed. She was treated with radiation therapy without response and died. There are few reports of erythematosus systemic lupus associated with primary central nervous system lymphoma.