Critical illness polyneuropathy: how often do we diagnose it?
Khilnani, G.C.; Bansal, R.; Malhotra, O.P.; Bhatia, M.
Indian Journal of Chest Diseases and Allied Sciences 45(3): 209-213
2003
ISSN/ISBN: 0377-9343 PMID: 12866641 Document Number: 561146
Neuromuscular weakness in critically ill patients is a diagnostic challenge. Critical illness polyneuropathy, an important cause of failure to wean from assisted ventilation is often missed due to lack of suspicion and initiative to undertake regular bedside neurological and electrophysiological examinations in critically ill patients. We report two cases who developed motor weakness while receiving mechanical ventilation in whom axonal neuropathy was diagnosed on electrophysiological studies, establishing a diagnosis of critical illness polyneuropathy. Both patients had evidence of sepsis and multiorgan failure. One case could be successfully weaned off and weakness improved while other succumbed to the underlying illness.