Drug induced anosmia with nifedipine
Kharoubi, S.
Presse Medicale 32(27): 1269-1272
2003
ISSN/ISBN: 0755-4982 PMID: 14506449 Document Number: 561141
Drug-induced dysosomia is rare and its prevalence difficult to estimate, notably because of the lack of satisfactory criteria of imputability. In a 59 year-old patient consulting for olfactory disorders that had progressed over the past 4 month, diagnosis of dysosomia secondary to the administration of nifedipine was maintained with a considerable score of imputability (negative clinical controls and partial regression of the disorder). Drugs used in cardiology represent one of the major therapeutic classes that can lead to dysfunction in smell and/or taste. These drugs are nifedipine reported in 1985, metoprolol (beta blocker), diltiazem and, more recently, enalapril.