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Preliminary clinical experience with the repetitive administration of levosimendan in patients with end-stage heart failure

Spargias, K.S.; Anifantakis, A.; Papadakis, M.; Iakovis, P.; Chatzigeorgiou, G.; Koutsogiannis, N.; Karatasakis, G.; Athanassopoulos, G.; Manginas, A.; Maounis, T.; Cokkinos, D.V.

Italian Heart Journal Official Journal of the Italian Federation of Cardiology 4(Suppl 2): 45s-49s

2003

ISSN/ISBN: 1129-471X
PMID: 14635370
Document Number: 559834
We present our preliminary clinical experience with the initial and repetitive administration of the novel inotropic agent levosimendan in a cohort of 20 patients with end-stage heart failure who were acutely decompensated or whose symptoms were refractory to the usual pharmacological treatments thus necessitating hospitalization. Repetitive levosimendan infusions were administered to 9 patients (minimum 2, maximum 8 pulses). The effects of this therapy on the symptomatic status, vital signs, hemodynamic performance and clinical outcomes are discussed.

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