Percutaneous absorption of various terpenes - menthol, camphene, limonene, isoborneol-acetate, alpha-pinene - from foam baths
Schäfer, R.; Schäfer, W.
Arzneimittel-Forschung 32(1): 56-58
1982
ISSN/ISBN: 0004-4172 PMID: 7199340 Document Number: 5593
The percutaneous absorptions of camphene, isoborneol-acetate, limonene, menthol and alpha-pinene as constituents of a foam bath (Pinimenthol) were measured on animals using radioactively labelled ingredients. Pharmacokinetic measurements showed maximum blood levels for all tested ingredients 10 min after the onset of percutaneous absorption. None of the ingredients was preferentially absorbed. Blood levels of all ingredients after 10 min of percutaneous absorption were a direct function of the size of the skin area involved.
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