Auditory brainstem response in children with iron deficiency anemia
Cankaya, H.; Oner, A.Faik.; Egeli, E.; Caksen, Hüseyin.; Uner, A.; Akçay, Gürbüz.
Acta Paediatrica Taiwanica 44(1): 21-24
2003
ISSN/ISBN: 1608-8115 PMID: 12800379 Document Number: 558669
A study was conducted, in Turkey, to investigate the neurosensorial influences with auditory brainstem response (ABR) in iron deficiency anaemia . ABR were recorded in 33 children with iron deficiency anaemia and in 31 healthy children (control group 1, 0-12 months, control group 2, 13-36 months, control group 3, 37-60 months) as a control group. The patients and controls were divided into 3 groups: group I, at 12 months of age, group II, 13-36 months, and group III, 37-60 months. In all groups, composed latency time, inter-peak latency, amplitude of peaks, I-V wave amplitude ratio and waveform were evaluated and compared with control groups. In group I, I-V interpeak latency increased compared with control group I (4.58 vs. 4.20 ms, P<0.05). In group II, Wave V latency time and III-V interpeak latency increased compared with control group 2 (6.21 ms vs. 5.63 ms. P<0.005 and 0, 48 vs. 0.22 P<0.005, respectively). In group III, wave I latency time increased compared with control group 3 (1.56 ms vs. 1.46 ms) (P<0.05). It is suggested that increases in ABR latencies might be explained by delayed maturation of myelinization, which requires iron, and/or by dysfunction of iron containing enzymes.