Characteristics of the K (+) -ion transport in the rat intestine following the use of natural zeolites as food additives
Gerasev, A.D.; Lukanina, S.N.; Sviatash, G.A.; Aĭzman, R.I.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 89(8): 972-981
2003
ISSN/ISBN: 0869-8139 PMID: 15119193 Document Number: 558609
Effects of zeolites as a food supplement have been studied on Wistar rats both in vivo perfusion experiments in the jejunum and distal colon and Rb fluxes through intestinal wall in the Ussing chamber. It has been found that zeolites decrease the K+ absorption and stimulate K+ secretion in the gut. This effect was due to inhibition of the apical N(+)-K(+)-ATPase and ouabain-sensitive Na(+)-independent K(+)-ATPase as well as the activation of the basolateral N(+)-K(+)-ATPase.