Second cancers associated with the cancer treatment and their possible control
Abe, T.; Nomura, K.
Nihon Rinsho. Japanese Journal of Clinical Medicine 61(6): 1045-1051
2003
ISSN/ISBN: 0047-1852 PMID: 12806958 Document Number: 557619
Second cancers induced by both alkylating agents and topoisomerase II inhibitors are reviewed with special reference to their distinct clinical features, incidences observed in the population at risk, cumulative risks, underlying molecular-genetic abnormalities, and also some detoxifying enzyme polymorphisms recently identified. Finally, it was discussed whether we can control these devastating diseases in the future.
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