BAY-43-9006 Bayer/Onyx
Lee, J.T.; McCubrey, J.A.
Current Opinion in Investigational Drugs 4(6): 757-763
2003
ISSN/ISBN: 1472-4472 PMID: 12901237 Document Number: 557586
Bayer and Onyx are developing BAY-43-9006, an oral cytostatic Raf kinase inhibitor for the potential treatment of colorectal and breast cancers, hepatocellular carcinoma and non-small-cell lung cancer, in addition to acute myelogenous leukemia, myelodysplastic syndrome and other cancers. A US IND was filed in May 2000 and by February 2003 BAY-43-9006 was in phase II trials, with phase III trials expected to begin later in 2003.