Metallophilia in the Ranvier's nodes of nerve fibers in rats of different strains (histochemical study)

Vshivtseva, V.V.; Zamuraev, I.N.; Lukashin, V.G.; Shiriaeva, N.V.

Morfologiia 124(4): 51-52

2003


ISSN/ISBN: 1026-3543
PMID: 14628556
Document Number: 556079
Myelinated nerve fibers formed by the processes of LV spinal ganglion neurons were studied in two lines of rats selected according to high and low thresholds of nerve system excitability to electric current. Before ultrastructural study the fibres have been treated with potassium pyroantimonate. It was demonstrated that specific dense precipitate was deposited in the nodes of Ranvier of the nerve fibers of rats with low excitability thresholds; this precipitate was not found in the fibers of rats with high thresholds. It is suggested that deposition of precipitate is indicative of a high density of sodium channels in neurilemma, i.e. of high functional activity of nerve fibers.

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