Inflammation in peritoneal dialysis

Ryckelynck, J.P.; Lobbedez, T.; Pujo, M.; el Haggan, W.; Hurault de Ligny, B.

Nephrologie 24(7): 367-370

2003


ISSN/ISBN: 0250-4960
PMID: 14650748
Document Number: 553746
In patients on peritoneal dialysis, peritoneal membrane alterations with inadequate peritoneal membrane function may be induced during long-term therapy. Chronic inflammation triggers malnutrition and atherosclerotic cardiovascular disease contributing to high mortality. The role of catheter, peritonitis and peritoneal dialysis fluids is argued. A neutral pH, a lesser presence of glucose degradation products generated during heat sterilization and accelerating the production of advanced glycosylation end-products (AGEs) could be reduced with better biocompatibility of peritoneal dialysis fluids.

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