Therapy of chronic viral hepatitis B
Vukobrat-Bijedić, Z.; Lacević, N.; Husić-Selimović, A.; Prohić, D.
Medicinski Arhiv 57(1 Suppl 2: 95-97
2003
ISSN/ISBN: 0025-8083 PMID: 15137245 Document Number: 553521
In chronic HBV infection, studies of outcome have shown that successful antiviral treatment undertaken early in course of diseases, may improve health and quality of life. Aims of treatment are: decrease of aminotransferase level to normal, histological necroinflammatory reduction, sustain loss of HbeAg and HBV DNA, antibodies on Hbe occurrence and loss of HbsAg with complete eradication of viral infection. Three therapeutical options are available: thymosine, lamivudine and standard interferon alpha. In future options, promising results are expecting from pegylated interferon, adefovire and entecavire.