Two cases of radiation-induced cancers 20 years after treatment of first malignancies
Parvanova, V.; Petkova, E.; Tzonevska, A.; Krasteva, E.
Journal of BUON Official Journal of the Balkan Union of Oncology 8(1): 69-71
2003
ISSN/ISBN: 1107-0625 PMID: 17415873 Document Number: 553433
Studies on radiation-induced breast and thyroid cancers have demonstrated that age at exposure is a major determinant of risk, with the greatest risk being for those irradiated as children and adolescents. In measuring the outcome of treatment, the ability to provide toxicity-free survival and minimal risk of second cancer may in future be regarded as important as achieving disease-free survival or local control. Herein we present two cases of secondary cancer with good treatment outcome that occurred 20 years after treatment for primary malignancies in childhood.