Clinical efficacy of combined anti-Helicobacter treatment of patients with duodenal ulcer
Kirika, N.V.; Bodrug, N.I.; Butorov, S.I.; Verbitskiĭ, O.N.; Ridlovskiĭ, A.I.; Butorov, I.V.; Lagutkin, D.I.; Martyniuk, L.I.
Klinicheskaia Meditsina 81(1): 37-39
2003
ISSN/ISBN: 0023-2149 PMID: 12650094 Document Number: 552165
84 patients with duodenal ulcer and positive by Helicobacter pylori (HP) were divided into two groups. Group 1 consisted of 42 patients who received omeprasol, metranidasol and clarithromycin. Group 2 of 42 patients received rovamycin instead of clarythromycin. The results of the study show that anti-HP regimen with rovamycin is superior to clarythromycin by main criteria (percent of healed ulcers, HP eradication, time to remission, recurrence rate, side effects rate). Thus, three-component therapy of patients with recurrent duodenal ulcer maintains intragastric acidity optimal for fast healing of ulcer defect.